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Dry Powder Comprised of Isoniazid-Loaded Nanoparticles of Hyaluronic Acid in Conjugation with Mannose-Anchored Chitosan for Macrophage-Targeted Pulmonary Administration in Tuberculosis

Marketed dosage forms fail to deliver anti-tubercular drugs directly to the lungs in pulmonary Tuberculosis (TB). Therefore, nanomediated isoniazid (INH)-loaded dry powder for inhalation (Nano-DPI) was developed for macrophage-targeted delivery in TB. Mannosylated chitosan (MC) and hyaluronic acid (...

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Detalles Bibliográficos
Autores principales:	Mukhtar, Mahwash, Csaba, Noemi, Robla, Sandra, Varela-Calviño, Rubén, Nagy, Attila, Burian, Katalin, Kókai, Dávid, Ambrus, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330414/ https://www.ncbi.nlm.nih.gov/pubmed/35893799 http://dx.doi.org/10.3390/pharmaceutics14081543

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