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The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity
The lack of resistance of plastic objects to various pathogens and their increasing activity in our daily life have made researchers develop polymeric materials with biocidal properties. Hence, this paper describes the thermoplastic composites of Polyamide 12 mixed with 1–5 wt % of the nanoparticles...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330415/ https://www.ncbi.nlm.nih.gov/pubmed/35893987 http://dx.doi.org/10.3390/polym14153025 |
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author | Latko-Durałek, Paulina Misiak, Michał Staniszewska, Monika Rosłoniec, Karina Grodzik, Marta Socha, Robert P. Krzan, Marcel Bażanów, Barbara Pogorzelska, Aleksandra Boczkowska, Anna |
author_facet | Latko-Durałek, Paulina Misiak, Michał Staniszewska, Monika Rosłoniec, Karina Grodzik, Marta Socha, Robert P. Krzan, Marcel Bażanów, Barbara Pogorzelska, Aleksandra Boczkowska, Anna |
author_sort | Latko-Durałek, Paulina |
collection | PubMed |
description | The lack of resistance of plastic objects to various pathogens and their increasing activity in our daily life have made researchers develop polymeric materials with biocidal properties. Hence, this paper describes the thermoplastic composites of Polyamide 12 mixed with 1–5 wt % of the nanoparticles of zinc, copper, and titanium oxides prepared by a twin-screw extrusion process and injection moulding. A satisfactory biocidal activity of polyamide 12 nanocomposites was obtained thanks to homogenously dispersed metal oxides in the polymer matrix and the wettability of the metal oxides by PA12. At 4 wt % of the metal oxides, the contact angles were the lowest and it resulted in obtaining the highest reduction rate of the Escherichia coli (87%), Candida albicans (53%), and Herpes simplex 1 (90%). The interactions of the nanocomposites with the fibroblasts show early apoptosis (11.85–27.79%), late apoptosis (0.81–5.04%), and necrosis (0.18–0.31%), which confirms the lack of toxicity of used metal oxides. Moreover, the used oxides affect slightly the thermal and rheological properties of PA12, which was determined by oscillatory rheology, thermogravimetric analysis, and differential scanning calorimetry. |
format | Online Article Text |
id | pubmed-9330415 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93304152022-07-29 The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity Latko-Durałek, Paulina Misiak, Michał Staniszewska, Monika Rosłoniec, Karina Grodzik, Marta Socha, Robert P. Krzan, Marcel Bażanów, Barbara Pogorzelska, Aleksandra Boczkowska, Anna Polymers (Basel) Article The lack of resistance of plastic objects to various pathogens and their increasing activity in our daily life have made researchers develop polymeric materials with biocidal properties. Hence, this paper describes the thermoplastic composites of Polyamide 12 mixed with 1–5 wt % of the nanoparticles of zinc, copper, and titanium oxides prepared by a twin-screw extrusion process and injection moulding. A satisfactory biocidal activity of polyamide 12 nanocomposites was obtained thanks to homogenously dispersed metal oxides in the polymer matrix and the wettability of the metal oxides by PA12. At 4 wt % of the metal oxides, the contact angles were the lowest and it resulted in obtaining the highest reduction rate of the Escherichia coli (87%), Candida albicans (53%), and Herpes simplex 1 (90%). The interactions of the nanocomposites with the fibroblasts show early apoptosis (11.85–27.79%), late apoptosis (0.81–5.04%), and necrosis (0.18–0.31%), which confirms the lack of toxicity of used metal oxides. Moreover, the used oxides affect slightly the thermal and rheological properties of PA12, which was determined by oscillatory rheology, thermogravimetric analysis, and differential scanning calorimetry. MDPI 2022-07-26 /pmc/articles/PMC9330415/ /pubmed/35893987 http://dx.doi.org/10.3390/polym14153025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Latko-Durałek, Paulina Misiak, Michał Staniszewska, Monika Rosłoniec, Karina Grodzik, Marta Socha, Robert P. Krzan, Marcel Bażanów, Barbara Pogorzelska, Aleksandra Boczkowska, Anna The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title | The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title_full | The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title_fullStr | The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title_full_unstemmed | The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title_short | The Composites of Polyamide 12 and Metal Oxides with High Antimicrobial Activity |
title_sort | composites of polyamide 12 and metal oxides with high antimicrobial activity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330415/ https://www.ncbi.nlm.nih.gov/pubmed/35893987 http://dx.doi.org/10.3390/polym14153025 |
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