Case Report: Subtotal Lymphoid and Total Marrow Irradiation as Bridge Therapy to CD19-Directed CAR T Cells in a Chemorefractory DLBCL With Leukemic Involvement

CAR T cell therapy has transformed the salvage approach for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL). Maintaining disease control before CAR T cell infusion during product manufacturing (so-called bridging therapy) is an important step to optimizing outcome. Among possible bridg...

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Detalles Bibliográficos
Autores principales: Saldi, Simonetta, Perriello, Vincenzo Maria, Falini, Lorenza, Ruggeri, Loredana, Fulcheri, Christian, Ciardelli, Sara, Innocente, Alessandra, Ballanti, Stelvio, Baffa, Nicodemo, Flenghi, Leonardo, Pierini, Antonio, Aristei, Cynthia, Falini, Brunangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330448/
https://www.ncbi.nlm.nih.gov/pubmed/35911683
http://dx.doi.org/10.3389/fimmu.2022.934700

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