Cargando…
Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer
Background: Elderly patients with stage I gastric cancer, a disease that is curable by surgery, easily develop long-term postoperative pneumonia (LTPP) within two years after surgery despite showing no active symptoms. The present study assessed whether or not LTPP determines the later prognosis amo...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330458/ https://www.ncbi.nlm.nih.gov/pubmed/35912008 http://dx.doi.org/10.7150/jca.71349 |
_version_ | 1784758165913468928 |
---|---|
author | Kamiya, Ayako Hayashi, Tsutomu Sakon, Ryota Ishizu, Kenichi Wada, Takeyuki Otsuki, Sho Yamagata, Yukinori Katai, Hitoshi Yoshikawa, Takaki |
author_facet | Kamiya, Ayako Hayashi, Tsutomu Sakon, Ryota Ishizu, Kenichi Wada, Takeyuki Otsuki, Sho Yamagata, Yukinori Katai, Hitoshi Yoshikawa, Takaki |
author_sort | Kamiya, Ayako |
collection | PubMed |
description | Background: Elderly patients with stage I gastric cancer, a disease that is curable by surgery, easily develop long-term postoperative pneumonia (LTPP) within two years after surgery despite showing no active symptoms. The present study assessed whether or not LTPP determines the later prognosis among elderly patients. Methods: We retrospectively examined patients >75 years old who underwent R0 gastrectomy for gastric cancer and were diagnosed with T1 disease at National Cancer Center Hospital between 2005 and 2012. LTPP was evaluated by chest computed tomography every year until two years after surgery. Results: Of the 3412 patients who underwent gastrectomy in our hospital during this period, 159 were included in this study. The elderly patients who developed LTPP had a worse prognosis than those who did not. Furthermore, their comorbidities and LTPP were significant independent risk factors for a poor prognosis. Patients who developed LTPP had a significantly higher risk of dying due to respiratory disease or cardiovascular disease than those without pneumonia. Conclusions: LTPP was significantly related to a poor survival and death from respiratory disease. To improve the prognosis, not only nutritional support but also exercise and rehabilitation program may be required for patients who develop LTPP within two years after surgery. |
format | Online Article Text |
id | pubmed-9330458 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-93304582022-07-29 Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer Kamiya, Ayako Hayashi, Tsutomu Sakon, Ryota Ishizu, Kenichi Wada, Takeyuki Otsuki, Sho Yamagata, Yukinori Katai, Hitoshi Yoshikawa, Takaki J Cancer Research Paper Background: Elderly patients with stage I gastric cancer, a disease that is curable by surgery, easily develop long-term postoperative pneumonia (LTPP) within two years after surgery despite showing no active symptoms. The present study assessed whether or not LTPP determines the later prognosis among elderly patients. Methods: We retrospectively examined patients >75 years old who underwent R0 gastrectomy for gastric cancer and were diagnosed with T1 disease at National Cancer Center Hospital between 2005 and 2012. LTPP was evaluated by chest computed tomography every year until two years after surgery. Results: Of the 3412 patients who underwent gastrectomy in our hospital during this period, 159 were included in this study. The elderly patients who developed LTPP had a worse prognosis than those who did not. Furthermore, their comorbidities and LTPP were significant independent risk factors for a poor prognosis. Patients who developed LTPP had a significantly higher risk of dying due to respiratory disease or cardiovascular disease than those without pneumonia. Conclusions: LTPP was significantly related to a poor survival and death from respiratory disease. To improve the prognosis, not only nutritional support but also exercise and rehabilitation program may be required for patients who develop LTPP within two years after surgery. Ivyspring International Publisher 2022-07-11 /pmc/articles/PMC9330458/ /pubmed/35912008 http://dx.doi.org/10.7150/jca.71349 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Research Paper Kamiya, Ayako Hayashi, Tsutomu Sakon, Ryota Ishizu, Kenichi Wada, Takeyuki Otsuki, Sho Yamagata, Yukinori Katai, Hitoshi Yoshikawa, Takaki Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title | Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title_full | Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title_fullStr | Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title_full_unstemmed | Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title_short | Prognostic Impact of Long-term Postoperative Pneumonia in Elderly Patients with Early Gastric Cancer |
title_sort | prognostic impact of long-term postoperative pneumonia in elderly patients with early gastric cancer |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330458/ https://www.ncbi.nlm.nih.gov/pubmed/35912008 http://dx.doi.org/10.7150/jca.71349 |
work_keys_str_mv | AT kamiyaayako prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT hayashitsutomu prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT sakonryota prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT ishizukenichi prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT wadatakeyuki prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT otsukisho prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT yamagatayukinori prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT kataihitoshi prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer AT yoshikawatakaki prognosticimpactoflongtermpostoperativepneumoniainelderlypatientswithearlygastriccancer |