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Two Step Selection for Bias in β Chain V-J Pairing
The β chain rearrangement in T cells is a two-step process where first D(β) and J(β) bind, and only then V(β) is joined to the complex. We here show that the frequency of human and mouse V(β) J(β) combinations deviates from the one expected based on each gene usage frequency. This bias is observed m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330483/ https://www.ncbi.nlm.nih.gov/pubmed/35911711 http://dx.doi.org/10.3389/fimmu.2022.906217 |