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A surrogate marker for very early-stage tau pathology is detectable by molecular magnetic resonance imaging

The abnormal phosphorylation of tau is a necessary precursor to the formation of tau fibrils, a marker of Alzheimer's disease. We hypothesize that hyperphosphorylative conditions may result in unique cell surface markers. We identify and demonstrate the utility of such surrogate markers to iden...

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Detalles Bibliográficos
Autores principales: Parekh, Parag, Mu, Qingshan, Badachhape, Andrew, Bhavane, Rohan, Srivastava, Mayank, Devkota, Laxman, Sun, Xianwei, Bhandari, Prajwal, Eriksen, Jason L., Tanifum, Eric, Ghaghada, Ketan, Annapragada, Ananth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330526/
https://www.ncbi.nlm.nih.gov/pubmed/35910789
http://dx.doi.org/10.7150/thno.72258