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DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis
Rationale: Doublecortin-like kinase 1 (DCLK1) is a serine/threonine kinase that selectively marks cancer stem-like cells (CSCs) and promotes malignant progression in colorectal cancer (CRC). However, the exact molecular mechanism by which DCLK1 drives the aggressive phenotype of cancer cells is inco...
Autores principales: | Kim, Jee-Heun, Park, So-Yeon, Jeon, So-El, Choi, Jang-Hyun, Lee, Choong-Jae, Jang, Tae-Young, Yun, Hyeon-Ji, Lee, Yuno, Kim, Pilho, Cho, Sang Hee, Lee, Ji Shin, Nam, Jeong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330537/ https://www.ncbi.nlm.nih.gov/pubmed/35910805 http://dx.doi.org/10.7150/thno.72037 |
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