Targeting the Ubiquinol-Reduction (Q(i)) Site of the Mitochondrial Cytochrome bc(1) Complex for the Development of Next Generation Quinolone Antimalarials

SIMPLE SUMMARY: Malaria is a life-threatening disease which infects millions of people a year via mosquito bites, particularly in developing countries. Although many malaria drugs are available in the market today, all of them have been challenged by drug-resistant variants. Developing a new drug to...

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Detalles Bibliográficos
Autores principales: Amporndanai, Kangsa, Pinthong, Nattapon, O’Neill, Paul M., Hong, W. David, Amewu, Richard K., Pidathala, Chandrakala, Berry, Neil G., Leung, Suet C., Ward, Stephen A., Biagini, Giancarlo A., Hasnain, S. Samar, Antonyuk, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330653/
https://www.ncbi.nlm.nih.gov/pubmed/35892964
http://dx.doi.org/10.3390/biology11081109

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