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Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

BACKGROUND: In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucleinopathies. It is unknown whether these variable results might be related to a differen...

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Detalles Bibliográficos
Autores principales: Bongianni, Matilde, Catalan, Mauro, Perra, Daniela, Fontana, Elena, Janes, Francesco, Bertolotti, Claudio, Sacchetto, Luca, Capaldi, Stefano, Tagliapietra, Matteo, Polverino, Paola, Tommasini, Valentina, Bellavita, Giulia, Kachoie, Elham Ataie, Baruca, Roberto, Bernardini, Andrea, Valente, Mariarosaria, Fiorini, Michele, Bronzato, Erika, Tamburin, Stefano, Bertolasi, Laura, Brozzetti, Lorenzo, Cecchini, Maria Paola, Gigli, Gianluigi, Monaco, Salvatore, Manganotti, Paolo, Zanusso, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330656/
https://www.ncbi.nlm.nih.gov/pubmed/35902902
http://dx.doi.org/10.1186/s40035-022-00311-3