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Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and Radiotherapy
Proliferating cells regularly experience replication stress caused by spontaneous DNA damage that results from endogenous reactive oxygen species (ROS), DNA sequences that can assume secondary and tertiary structures, and collisions between opposing transcription and replication machineries. Cancer...
Autor principal: | Nickoloff, Jac A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330692/ https://www.ncbi.nlm.nih.gov/pubmed/35897913 http://dx.doi.org/10.3390/molecules27154736 |
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