Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface

[Image: see text] The capacity to efficiently deliver the gene-editing enzyme complex to target cells is favored over other forms of gene delivery as it offers one-time hit-and-run gene editing, thus improving precision and safety and reducing potential immunogenicity against edited cells in clinica...

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Detalles Bibliográficos
Autores principales: Lu, Zhi Hong, Li, Jie, Dmitriev, Igor P., Kashentseva, Elena A., Curiel, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330763/
https://www.ncbi.nlm.nih.gov/pubmed/35749339
http://dx.doi.org/10.1021/acsnano.2c00909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330763/
https://www.ncbi.nlm.nih.gov/pubmed/35749339
http://dx.doi.org/10.1021/acsnano.2c00909

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