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Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface
[Image: see text] The capacity to efficiently deliver the gene-editing enzyme complex to target cells is favored over other forms of gene delivery as it offers one-time hit-and-run gene editing, thus improving precision and safety and reducing potential immunogenicity against edited cells in clinica...
Autores principales: | Lu, Zhi Hong, Li, Jie, Dmitriev, Igor P., Kashentseva, Elena A., Curiel, David T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330763/ https://www.ncbi.nlm.nih.gov/pubmed/35749339 http://dx.doi.org/10.1021/acsnano.2c00909 |
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