Reversible Thiol Oxidation Increases Mitochondrial Electron Transport Complex Enzyme Activity but Not Respiration in Cardiomyocytes from Patients with End-Stage Heart Failure

Cardiomyocyte dysfunction in patients with end-stage heart failure with reduced ejection fraction (HFrEF) stems from mitochondrial dysfunction, which contributes to an energetic crisis. Mitochondrial dysfunction reportedly relates to increased markers of oxidative stress, but the impact of reversibl...

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Detalles Bibliográficos
Autores principales: Kumar, Ravi A., Thome, Trace, Sharaf, Omar M., Ryan, Terence E., Arnaoutakis, George J., Jeng, Eric I., Ferreira, Leonardo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330889/
https://www.ncbi.nlm.nih.gov/pubmed/35892589
http://dx.doi.org/10.3390/cells11152292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330889/
https://www.ncbi.nlm.nih.gov/pubmed/35892589
http://dx.doi.org/10.3390/cells11152292

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