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Reversible Thiol Oxidation Increases Mitochondrial Electron Transport Complex Enzyme Activity but Not Respiration in Cardiomyocytes from Patients with End-Stage Heart Failure
Cardiomyocyte dysfunction in patients with end-stage heart failure with reduced ejection fraction (HFrEF) stems from mitochondrial dysfunction, which contributes to an energetic crisis. Mitochondrial dysfunction reportedly relates to increased markers of oxidative stress, but the impact of reversibl...
Autores principales: | Kumar, Ravi A., Thome, Trace, Sharaf, Omar M., Ryan, Terence E., Arnaoutakis, George J., Jeng, Eric I., Ferreira, Leonardo F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330889/ https://www.ncbi.nlm.nih.gov/pubmed/35892589 http://dx.doi.org/10.3390/cells11152292 |
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