Cargando…
A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish
Mitochondria are a dynamic eukaryotic innovation that play diverse roles in biology and disease. The mitochondrial genome is remarkably conserved in all vertebrates, encoding the same 37-gene set and overall genomic structure, ranging from 16,596 base pairs (bp) in the teleost zebrafish (Danio rerio...
Autores principales: | Sabharwal, Ankit, Campbell, Jarryd M., Schwab, Tanya L., WareJoncas, Zachary, Wishman, Mark D., Ata, Hirotaka, Liu, Wiebin, Ichino, Noriko, Hunter, Danielle E., Bergren, Jake D., Urban, Mark D., Urban, Rhianna M., Holmberg, Shannon R., Kar, Bibekananda, Cook, Alex, Ding, Yonghe, Xu, Xiaolei, Clark, Karl J., Ekker, Stephen C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331066/ https://www.ncbi.nlm.nih.gov/pubmed/35893052 http://dx.doi.org/10.3390/genes13081317 |
Ejemplares similares
-
The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo
por: Sabharwal, Ankit, et al.
Publicado: (2021) -
Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality
por: Sabharwal, Ankit, et al.
Publicado: (2022) -
Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities
por: Kar, Bibekananda, et al.
Publicado: (2023) -
Building the vertebrate codex using the gene breaking protein trap library
por: Ichino, Noriko, et al.
Publicado: (2020) -
An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines
por: Kar, Bibekananda, et al.
Publicado: (2022)