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Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan
As the population of older adults grows, so will the prevalence of aging-related conditions, including memory impairments and sleep disturbances, both of which are more common among women. Compared to older men, older women are up to twice as likely to experience sleep disturbances and are at a high...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331168/ https://www.ncbi.nlm.nih.gov/pubmed/35912083 http://dx.doi.org/10.3389/fnagi.2022.800278 |
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author | Harrington, Yasmin A. Parisi, Jeanine M. Duan, Daisy Rojo-Wissar, Darlynn M. Holingue, Calliope Spira, Adam P. |
author_facet | Harrington, Yasmin A. Parisi, Jeanine M. Duan, Daisy Rojo-Wissar, Darlynn M. Holingue, Calliope Spira, Adam P. |
author_sort | Harrington, Yasmin A. |
collection | PubMed |
description | As the population of older adults grows, so will the prevalence of aging-related conditions, including memory impairments and sleep disturbances, both of which are more common among women. Compared to older men, older women are up to twice as likely to experience sleep disturbances and are at a higher risk of cognitive decline and Alzheimer’s disease and related dementias (ADRD). These sex differences may be attributed in part to fluctuations in levels of female sex hormones (i.e., estrogen and progesterone) that occur across the adult female lifespan. Though women tend to experience the most significant sleep and memory problems during the peri-menopausal period, changes in memory and sleep have also been observed across the menstrual cycle and during pregnancy. Here, we review current knowledge on the interrelationships among female sex hormones, sleep, and memory across the female lifespan, propose possible mediating and moderating mechanisms linking these variables and describe implications for ADRD risk in later life. |
format | Online Article Text |
id | pubmed-9331168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93311682022-07-29 Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan Harrington, Yasmin A. Parisi, Jeanine M. Duan, Daisy Rojo-Wissar, Darlynn M. Holingue, Calliope Spira, Adam P. Front Aging Neurosci Aging Neuroscience As the population of older adults grows, so will the prevalence of aging-related conditions, including memory impairments and sleep disturbances, both of which are more common among women. Compared to older men, older women are up to twice as likely to experience sleep disturbances and are at a higher risk of cognitive decline and Alzheimer’s disease and related dementias (ADRD). These sex differences may be attributed in part to fluctuations in levels of female sex hormones (i.e., estrogen and progesterone) that occur across the adult female lifespan. Though women tend to experience the most significant sleep and memory problems during the peri-menopausal period, changes in memory and sleep have also been observed across the menstrual cycle and during pregnancy. Here, we review current knowledge on the interrelationships among female sex hormones, sleep, and memory across the female lifespan, propose possible mediating and moderating mechanisms linking these variables and describe implications for ADRD risk in later life. Frontiers Media S.A. 2022-07-14 /pmc/articles/PMC9331168/ /pubmed/35912083 http://dx.doi.org/10.3389/fnagi.2022.800278 Text en Copyright © 2022 Harrington, Parisi, Duan, Rojo-Wissar, Holingue and Spira. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Aging Neuroscience Harrington, Yasmin A. Parisi, Jeanine M. Duan, Daisy Rojo-Wissar, Darlynn M. Holingue, Calliope Spira, Adam P. Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title | Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title_full | Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title_fullStr | Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title_full_unstemmed | Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title_short | Sex Hormones, Sleep, and Memory: Interrelationships Across the Adult Female Lifespan |
title_sort | sex hormones, sleep, and memory: interrelationships across the adult female lifespan |
topic | Aging Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331168/ https://www.ncbi.nlm.nih.gov/pubmed/35912083 http://dx.doi.org/10.3389/fnagi.2022.800278 |
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