Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

We have recently developed a new synthetic methodology that provided both N-aryl-5-hydroxytriazoles and N-pyridine-4-alkyl triazoles. A selection of these products was carried through virtual screening towards targets that are contemporary and validated for drug discovery and development. This study...

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Detalles Bibliográficos
Autores principales: Pacifico, Roberta, Del Gaudio, Nunzio, Bove, Guglielmo, Altucci, Lucia, Siragusa, Lydia, Cruciani, Gabriele, Ruvo, Menotti, Bellavita, Rosa, Grieco, Paolo, Adamo, Mauro F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331200/
https://www.ncbi.nlm.nih.gov/pubmed/35880250
http://dx.doi.org/10.1080/14756366.2022.2097447

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