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Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial
Background: There is limited information on the effectiveness of 38% silver diamine fluoride (SDF) in managing enamel caries. Objective: This study aimed to compare effectiveness of 38% SDF and 5% Sodium fluoride (NaF) varnish in arresting enamel caries in young children when applied semiannually ov...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331268/ https://www.ncbi.nlm.nih.gov/pubmed/35897363 http://dx.doi.org/10.3390/ijerph19158992 |
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author | Phonghanyudh, Araya Duangthip, Duangporn Mabangkhru, Sirinan Jirarattanasopha, Varangkanar |
author_facet | Phonghanyudh, Araya Duangthip, Duangporn Mabangkhru, Sirinan Jirarattanasopha, Varangkanar |
author_sort | Phonghanyudh, Araya |
collection | PubMed |
description | Background: There is limited information on the effectiveness of 38% silver diamine fluoride (SDF) in managing enamel caries. Objective: This study aimed to compare effectiveness of 38% SDF and 5% Sodium fluoride (NaF) varnish in arresting enamel caries in young children when applied semiannually over 18 months. Methods: A randomized controlled trial was conducted on children aged 1–3 years who had at least one active carious surface. They were allocated into two groups: Group 1 (38% SDF) and Group 2 (5% NaF varnish). Visual-tactile examination was used to assess extent of carious lesions. Enamel caries that did not progress to dentin were classified as having caries arrest. Intention-to-treat analysis was performed. Results: At baseline, 290 children with 1974 tooth surfaces with enamel caries were recruited. Caries arrest rates at the tooth surface level in Group 1 and Group 2 were 59.1% and 58.8%, respectively (p = 0.873), at 18 months. The multilevel logistic regression analysis revealed that tooth position, tooth surface, extent of enamel caries at baseline, caries experience, and brushing with fluoride toothpaste influenced caries arrest (p < 0.05). Conclusion: The semiannual application of 38% SDF and 5% NaF varnish had comparable effectiveness in arresting enamel caries in primary teeth. |
format | Online Article Text |
id | pubmed-9331268 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93312682022-07-29 Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial Phonghanyudh, Araya Duangthip, Duangporn Mabangkhru, Sirinan Jirarattanasopha, Varangkanar Int J Environ Res Public Health Article Background: There is limited information on the effectiveness of 38% silver diamine fluoride (SDF) in managing enamel caries. Objective: This study aimed to compare effectiveness of 38% SDF and 5% Sodium fluoride (NaF) varnish in arresting enamel caries in young children when applied semiannually over 18 months. Methods: A randomized controlled trial was conducted on children aged 1–3 years who had at least one active carious surface. They were allocated into two groups: Group 1 (38% SDF) and Group 2 (5% NaF varnish). Visual-tactile examination was used to assess extent of carious lesions. Enamel caries that did not progress to dentin were classified as having caries arrest. Intention-to-treat analysis was performed. Results: At baseline, 290 children with 1974 tooth surfaces with enamel caries were recruited. Caries arrest rates at the tooth surface level in Group 1 and Group 2 were 59.1% and 58.8%, respectively (p = 0.873), at 18 months. The multilevel logistic regression analysis revealed that tooth position, tooth surface, extent of enamel caries at baseline, caries experience, and brushing with fluoride toothpaste influenced caries arrest (p < 0.05). Conclusion: The semiannual application of 38% SDF and 5% NaF varnish had comparable effectiveness in arresting enamel caries in primary teeth. MDPI 2022-07-24 /pmc/articles/PMC9331268/ /pubmed/35897363 http://dx.doi.org/10.3390/ijerph19158992 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Phonghanyudh, Araya Duangthip, Duangporn Mabangkhru, Sirinan Jirarattanasopha, Varangkanar Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title | Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title_full | Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title_fullStr | Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title_full_unstemmed | Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title_short | Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial |
title_sort | is silver diamine fluoride effective in arresting enamel caries? a randomized clinical trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331268/ https://www.ncbi.nlm.nih.gov/pubmed/35897363 http://dx.doi.org/10.3390/ijerph19158992 |
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