Cargando…
MGRN1 as a Phenotypic Determinant of Human Melanoma Cells and a Potential Biomarker
Mahogunin Ring Finger 1 (MGRN1), a ubiquitin ligase expressed in melanocytes, interacts with the α melanocyte-stimulating hormone receptor, a well-known melanoma susceptibility gene. Previous studies showed that MGRN1 modulates the phenotype of mouse melanocytes and melanoma cells, with effects on p...
Autores principales: | Abrisqueta, Marta, Cerdido, Sonia, Sánchez-Beltrán, José, Martínez-Vicente, Idoya, Herraiz, Cecilia, Lambertos, Ana, Olivares, Conchi, Sevilla, Arrate, Alonso, Santos, Boyano, María Dolores, García-Borrón, José Carlos, Jiménez-Cervantes, Celia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331370/ https://www.ncbi.nlm.nih.gov/pubmed/35892921 http://dx.doi.org/10.3390/life12081118 |
Ejemplares similares
-
A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA
por: Cerdido, Sonia, et al.
Publicado: (2023) -
Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells
por: Martínez-Vicente, Idoya, et al.
Publicado: (2020) -
Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor
por: Herraiz, Cecilia, et al.
Publicado: (2015) -
Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells
por: Sirés-Campos, Julia, et al.
Publicado: (2021) -
E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion
por: Benvegnù, Stefano, et al.
Publicado: (2017)