The Identification by Exome Sequencing of Candidate Genes in BRCA-Negative Tunisian Patients at a High Risk of Hereditary Breast/Ovarian Cancer

(1) Background: Germline variants in BRCA1/BRCA2 genes explain about 20% of hereditary breast/ovarian cancer (HBOC) cases. In the present paper, we aim to identify genetic determinants in BRCA-negative families from the South of Tunisia. (2) Methods: Exome Sequencing (ES) was performed on the lympho...

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Detalles Bibliográficos
Autores principales: BenAyed-Guerfali, Dorra, Kifagi, Chamseddine, BenKridis-Rejeb, Wala, Ammous-Boukhris, Nihel, Ayedi, Wajdi, Khanfir, Afef, Daoud, Jamel, Mokdad-Gargouri, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331434/
https://www.ncbi.nlm.nih.gov/pubmed/35893033
http://dx.doi.org/10.3390/genes13081296

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