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Insights into Domain Organization and Regulatory Mechanism of Cystathionine Beta-Synthase from Toxoplasma gondii

Cystathionine beta-synthase (CBS) is a key regulator of homocysteine metabolism. Although eukaryotic CBS have a similar domain architecture with a catalytic core and a C-terminal Bateman module, their regulation varies widely across phyla. In human CBS (HsCBS), the C-terminus has an autoinhibitory e...

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Detalles Bibliográficos
Autores principales: Conter, Carolina, Fruncillo, Silvia, Favretto, Filippo, Fernández-Rodríguez, Carmen, Dominici, Paola, Martínez-Cruz, Luis Alfonso, Astegno, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331509/
https://www.ncbi.nlm.nih.gov/pubmed/35897745
http://dx.doi.org/10.3390/ijms23158169