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Identification of Malignant Cell Populations Associated with Poor Prognosis in High-Grade Serous Ovarian Cancer Using Single-Cell RNA Sequencing

SIMPLE SUMMARY: Ovarian cancer has a high recurrence rate (~75%), and tumor heterogeneity is associated with such tumor recurrence. However, it is still poorly understood in ovarian cancer. To reveal tumor heterogeneity, we performed single-cell RNA sequencing (RNA-seq) of serous ovarian cancer cell...

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Detalles Bibliográficos
Autores principales: Sumitani, Naoki, Ishida, Kyoso, Sawada, Kenjiro, Kimura, Tadashi, Kaneda, Yasufumi, Nimura, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331511/
https://www.ncbi.nlm.nih.gov/pubmed/35892844
http://dx.doi.org/10.3390/cancers14153580