Intracellular alpha-fetoprotein mitigates hepatocyte apoptosis and necroptosis by inhibiting endoplasmic reticulum stress

BACKGROUND: Endoplasmic reticulum (ER) stress contributes to the pathogenesis of chronic liver diseases, but how hepatocytes respond to ER stress has not been clarified. Alpha-fetoprotein (AFP) is secreted by hepatoma cells and elevated levels of serum AFP are associated with development of liver ma...

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Detalles Bibliográficos
Autores principales: Chen, Yun-Fen, Liu, Si-Ying, Cheng, Qi-Jiao, Wang, Yu-Jiao, Chen, Shuang, Zhou, Yi-Yang, Liu, Xia, Jiang, Zhi-Gang, Zhong, Wei-Wei, He, Yi-Huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331527/
https://www.ncbi.nlm.nih.gov/pubmed/36051342
http://dx.doi.org/10.3748/wjg.v28.i26.3201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331527/
https://www.ncbi.nlm.nih.gov/pubmed/36051342
http://dx.doi.org/10.3748/wjg.v28.i26.3201

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