Cargando…

Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) involves various structural and functional changes because of chronic glycemic assault and kidney failure. Proteinuria is an early clinical manifestation of DN, but the associated pathogenesis remains elusive. This study aimed to investigate the role of microtub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Lingfei, Feng, Yanhai, Zhang, Junhui, Zhang, Qiong, Ren, Jun, Sun, Cheng, Li, Shujing, Lei, Xia, Luo, Gaoxing, Hu, Jiongyu, Huang, Yuesheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331595/ https://www.ncbi.nlm.nih.gov/pubmed/35902952 http://dx.doi.org/10.1186/s12964-022-00883-7

Ejemplares similares

Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction
por: Li, Lingfei, et al.
Publicado: (2019)

Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia
por: Feng, Yanhai, et al.
Publicado: (2023)

Correction: Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia
por: Feng, Yanhai, et al.
Publicado: (2023)

Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice
por: Li, Lingfei, et al.
Publicado: (2018)

Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation
por: Zhang, Junhui, et al.
Publicado: (2019)

Phosphorylation of Microtubule- Associated Protein 4 Promotes Hypoxic Endothelial Cell Migration and Proliferation
por: Zhang, Junhui, et al.
Publicado: (2019)

Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice
por: Lv, Zhimei, et al.
Publicado: (2018)

P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury
por: Li, Lingfei, et al.
Publicado: (2015)

Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement
por: Huang, Na, et al.
Publicado: (2018)

Role of the podocyte in proteinuria
por: Menzel, Sylvia, et al.
Publicado: (2011)

MAP4 as a New Candidate in Cardiovascular Disease
por: Li, Lingfei, et al.
Publicado: (2020)

High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway
por: Li, Lingfei, et al.
Publicado: (2019)

Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury
por: Li, Lingfei, et al.
Publicado: (2019)

Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy
por: Chang, Meiying, et al.
Publicado: (2021)

Inwardly rectifying potassium channel 5.1: Structure, function, and possible roles in diseases
por: Zhang, Junhui, et al.
Publicado: (2020)

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling
por: Liu, Min, et al.
Publicado: (2017)

IgA nephropathy with podocytic infolding glomerulopathy
por: Wang, Zhouyang, et al.
Publicado: (2023)

Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation
por: He, Ting, et al.
Publicado: (2015)

Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy
por: Fujino, Takayuki, et al.
Publicado: (2016)

Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates Proteinuria
por: Ahmadi, Amin, et al.
Publicado: (2019)

Comparison between outcomes of IgA nephropathy with nephrotic-range proteinuria and nephrotic syndrome: do podocytes play a role?
por: Chen, Yizhen, et al.
Publicado: (2022)

α- and β-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy
por: Ferrandi, Mara, et al.
Publicado: (2009)

Gα12 Activation in Podocytes Leads to Cumulative Changes in Glomerular Collagen Expression, Proteinuria and Glomerulosclerosis
por: Boucher, Ilene, et al.
Publicado: (2012)

Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration
por: Zhang, Junhui, et al.
Publicado: (2019)

Author Correction: Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration
por: Zhang, Junhui, et al.
Publicado: (2019)

Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury
por: Zhou, Han, et al.
Publicado: (2017)

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes
por: Mao, Jianhua, et al.
Publicado: (2013)

Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration
por: Ren, Jiafa, et al.
Publicado: (2021)

Editorial: Podocyte Pathology and Nephropathy
por: Lewko, Barbara, et al.
Publicado: (2015)

Retraction Note: Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates Proteinuria
por: Ahmadi, Amin, et al.
Publicado: (2021)

1,25-Dihydroxyvitamin D(3) Inhibits Podocyte uPAR Expression and Reduces Proteinuria
por: Ma, Jianchao, et al.
Publicado: (2013)

Saxagliptin Attenuates Albuminuria by Inhibiting Podocyte Epithelial- to-Mesenchymal Transition via SDF-1α in Diabetic Nephropathy
por: Chang, Yun-peng, et al.
Publicado: (2017)

Podocytes and Proteinuria in ANCA-Associated Glomerulonephritis: A Case-Control Study
por: van Daalen, Emma E., et al.
Publicado: (2019)

New insight into podocyte slit diaphragm, a therapeutic target of proteinuria
por: Kawachi, Hiroshi, et al.
Publicado: (2020)

Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria
por: Nishad, Rajkishor, et al.
Publicado: (2021)

Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria
por: Nishad, Rajkishor, et al.
Publicado: (2021)

Diabetic Nephropathy: Proteinuria, Inflammation, and Fibrosis
por: Zheng, Shirong, et al.
Publicado: (2016)

SuPAR mediates viral response proteinuria by rapidly changing podocyte function
por: Wei, Changli, et al.
Publicado: (2023)

Seasonal proteinuria changes in IgA nephropathy patients after proteinuria remission
por: Inagaki, Koji, et al.
Publicado: (2017)

Metadherin facilitates podocyte apoptosis in diabetic nephropathy
por: Liu, Wen-Ting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0e32eu4cs6mosv20pfhlidqm2f