Cargando…

Evaluation of Toxicity and Efficacy of Inotodiol as an Anti-Inflammatory Agent Using Animal Model

Chaga mushroom (Inonotus obliquus) comprises polyphenolic compounds, triterpenoids, polysaccharides, and sterols. Among the triterpenoid components, inotodiol has been broadly examined because of its various biological activities. The purpose of this study is to examine inotodiol from a safety point...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Thi Minh Nguyet, Ban, So-Young, Park, Kyu-Been, Lee, Chang-Kyu, Lee, Seoung-Woo, Lee, Young-Jin, Baek, Su-Min, Park, Jin-Kyu, Nguyen, My Tuyen Thi, Kim, Jaehan, Park, Jihyun, Park, Jong-Tae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331631/ https://www.ncbi.nlm.nih.gov/pubmed/35897881 http://dx.doi.org/10.3390/molecules27154704

Ejemplares similares

Isolation, Physicochemical Characterization, and Biological Properties of Inotodiol, the Potent Pharmaceutical Oxysterol from Chaga Mushroom
por: Nguyen, Phu Cuong, et al.
Publicado: (2023)

Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes, HaCaT Cells, against Inflammatory and Oxidative Stresses
por: Park, Jihyun, et al.
Publicado: (2023)

Preventive effects of inotodiol on polyinosinic–polycytidylic acid-induced inflammation in human dermal fibroblasts
por: Won, Gun-Woo, et al.
Publicado: (2023)

Variation of Triterpenic Acids in 12 Wild Syzygium formosum and Anti-Inflammation Activity on Human Keratinocyte HaCaT
por: Park, Hyun-ah, et al.
Publicado: (2021)

Inotodiol From Inonotus obliquus Chaga Mushroom Induces Atypical Maturation in Dendritic Cells
por: Maza, Perry Ayn Mayson A., et al.
Publicado: (2021)

Oxidative Stress Related to Plasmalemmal and Mitochondrial Phosphate Transporters in Vascular Calcification
por: Nguyen, Nhung Thi, et al.
Publicado: (2022)

Inhibition of mitochondrial phosphate carrier prevents high phosphate-induced superoxide generation and vascular calcification
por: Thi Nguyen, Nhung, et al.
Publicado: (2023)

Senescence Marker Protein 30 (SMP30): A Novel Pan-Species Diagnostic Marker for the Histopathological Diagnosis of Breast Cancer in Humans and Animals
por: Baek, Su-Min, et al.
Publicado: (2021)

A Novel Bioanalytical Method for Determination of Inotodiol Isolated from Inonotus Obliquus and Its Application to Pharmacokinetic Study
por: Kim, Jin Hyeok, et al.
Publicado: (2021)

Anti-Fibrotic Effect of Synthetic Noncoding Decoy ODNs for TFEB in an Animal Model of Chronic Kidney Disease
por: Lee, Sun-Jae, et al.
Publicado: (2022)

Nonspecific Bronchoprovocation Test
por: Lee, Myoung Kyu, et al.
Publicado: (2017)

Disrupted-in-schizophrenia 1 enhances the quality of circadian rhythm by stabilizing BMAL1
por: Lee, Su Been, et al.
Publicado: (2021)

Effects of steaming on saponin compositions and antiproliferative activity of Vietnamese ginseng
por: Le, Thi Hong Van, et al.
Publicado: (2015)

Ultrasound Image-Based Diagnosis of Malignant Thyroid Nodule Using Artificial Intelligence
por: Nguyen, Dat Tien, et al.
Publicado: (2020)

Thyroid Hormone Induces Ca(2+)-Mediated Mitochondrial Activation in Brown Adipocytes
por: Nguyen, Minh-Hanh Thi, et al.
Publicado: (2021)

Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats
por: Lee, Jong Rok, et al.
Publicado: (2009)

Therapeutic Agent-Loaded Fibrous Scaffolds for Biomedical Applications
por: Park, Dongsik, et al.
Publicado: (2023)

Case report: Fatal neonatal sepsis associated with Escherichia fergusonii infection in a common bottlenose dolphin (Tursiops truncatus)
por: Baek, Su-Min, et al.
Publicado: (2023)

Control of the growth and development of murine preantral follicles in a biomimetic ovary using a decellularized porcine scaffold
por: Park, Eun young, et al.
Publicado: (2023)

Feline-type cystic basal cell tumor filled with abundant melanin pigment-rich fluid in a dog
por: LEE, Seoung-Woo, et al.
Publicado: (2018)

Experimental and numerical simulation on dynamics of a moored semi-submersible in various wave directions
por: Diep Nguyen, Thi Thanh, et al.
Publicado: (2022)

Kalopanacis Cortex extract-capped gold nanoparticles activate NRF2 signaling and ameliorate damage in human neuronal SH-SY5Y cells exposed to oxygen–glucose deprivation and reoxygenation
por: Park, Sun Young, et al.
Publicado: (2017)

Identification of Anthocyanin Compounds in Butterfly Pea Flowers (Clitoria ternatea L.) by Ultra Performance Liquid Chromatography/Ultraviolet Coupled to Mass Spectrometry
por: Thuy, Nguyen Minh, et al.
Publicado: (2021)

Single-Stage Operation for Giant Schwannoma at the Craniocervical Junction with Minimal Laminectomy: A Case Report and Literature Review
por: Yoon, Sun, et al.
Publicado: (2016)

Response Methodology Optimization and Artificial Neural Network Modeling for the Removal of Sulfamethoxazole Using an Ozone–Electrocoagulation Hybrid Process
por: Nghia, Nguyen Trong, et al.
Publicado: (2023)

Furan-2,5- and Furan-2,3-dicarboxylate Esters Derived from Marine Biomass as Plasticizers for Poly(vinyl chloride)
por: Nguyen, TanPhat, et al.
Publicado: (2019)

Increasing trend in rhegmatogenous retinal detachment in Korea from 2004 to 2015
por: Park, Jun Young, et al.
Publicado: (2021)

Hepatic Cellular Distribution of Silica Nanoparticles by Surface Energy Modification
por: Lee, A-Rang, et al.
Publicado: (2019)

Embryo Aggregation Promotes Derivation Efficiency of Outgrowths from Porcine Blastocysts
por: Lee, Sang-Goo, et al.
Publicado: (2015)

Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity
por: Dolan, Laurie C., et al.
Publicado: (2022)

Extramedullary plasmacytoma of the oral cavity metastasising to both kidneys in a dog
por: Park, Kyung Ho, et al.
Publicado: (2023)

Toxicity of the recombinant human hyaluronidase ALT-BC4 on embryonic development
por: Lee, Ji Hye, et al.
Publicado: (2021)

Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans
por: Kim, So-Hyeon, et al.
Publicado: (2019)

Sniffer worm, C. elegans, as a toxicity evaluation model organism with sensing and locomotion abilities
por: Kim, Jun Sung, et al.
Publicado: (2023)

Unraveling the Janus-Faced Role of Autophagy in Hepatocellular Carcinoma: Implications for Therapeutic Interventions
por: Nguyen, Thi Ha, et al.
Publicado: (2023)

Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells
por: Park, So Young, et al.
Publicado: (2016)

Acute Dermal Toxicity Study of Bee Venom (Apis mellifera L.) in Rats
por: Han, Sang Mi, et al.
Publicado: (2012)

All-graphene-battery: bridging the gap between supercapacitors and lithium ion batteries
por: Kim, Haegyeom, et al.
Publicado: (2014)

PAIDB v2.0: exploration and analysis of pathogenicity and resistance islands
por: Yoon, Sung Ho, et al.
Publicado: (2014)

Acanthopanax sessiliflorus stem confers increased resistance to environmental stresses and lifespan extension in Caenorhabditis elegans
por: Park, Jin-Kook, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ajeqjnhc358n7m6f0a8v7hpvjt