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What Do We Know about Spondylodiscitis in Children? A Retrospective Study

Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a thi...

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Autores principales: Yagdiran, Ayla, Meyer-Schwickerath, Charlotte, Wolpers, Raphael, Otto-Lambertz, Christina, Mehler, Katrin, Oberthür, Andre, Kernich, Nikolaus, Eysel, Peer, Jung, Norma, Zarghooni, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331686/
https://www.ncbi.nlm.nih.gov/pubmed/35892606
http://dx.doi.org/10.3390/children9081103
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author Yagdiran, Ayla
Meyer-Schwickerath, Charlotte
Wolpers, Raphael
Otto-Lambertz, Christina
Mehler, Katrin
Oberthür, Andre
Kernich, Nikolaus
Eysel, Peer
Jung, Norma
Zarghooni, Kourosh
author_facet Yagdiran, Ayla
Meyer-Schwickerath, Charlotte
Wolpers, Raphael
Otto-Lambertz, Christina
Mehler, Katrin
Oberthür, Andre
Kernich, Nikolaus
Eysel, Peer
Jung, Norma
Zarghooni, Kourosh
author_sort Yagdiran, Ayla
collection PubMed
description Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a third-level hospital (2009–2019) in PSD and compare these with adult spondylodiscitis (ASD). Of a total of 10 PSD patients, most of the infants presented with unspecific pain such as hip pain or a limping, misleading an adequate diagnosis of spine origin. Eight patients could be treated conservatively whereas surgery was performed in two cases with one case of tuberculous PSD (tPSD). The causative agent was detected in three of the patients. The diagnosis of PSD is often difficult since clinical symptoms are unspecific and causative pathogens often remain undetected. Nevertheless, empirical anti-infective therapy also seems to be effective. Based on recent studies, clinicians should be encouraged to keep the duration of anti-infective therapy in children short. Since comorbidities are not presented in PSD it is unclear which children suffer from PSD; thus, studies are necessary to identify predisposing factors for PSD. In our study, PSD differs from ASD in diagnostic and especially in therapeutic aspects. Therefore, specific guidelines for PSD would be desirable.
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spelling pubmed-93316862022-07-29 What Do We Know about Spondylodiscitis in Children? A Retrospective Study Yagdiran, Ayla Meyer-Schwickerath, Charlotte Wolpers, Raphael Otto-Lambertz, Christina Mehler, Katrin Oberthür, Andre Kernich, Nikolaus Eysel, Peer Jung, Norma Zarghooni, Kourosh Children (Basel) Article Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a third-level hospital (2009–2019) in PSD and compare these with adult spondylodiscitis (ASD). Of a total of 10 PSD patients, most of the infants presented with unspecific pain such as hip pain or a limping, misleading an adequate diagnosis of spine origin. Eight patients could be treated conservatively whereas surgery was performed in two cases with one case of tuberculous PSD (tPSD). The causative agent was detected in three of the patients. The diagnosis of PSD is often difficult since clinical symptoms are unspecific and causative pathogens often remain undetected. Nevertheless, empirical anti-infective therapy also seems to be effective. Based on recent studies, clinicians should be encouraged to keep the duration of anti-infective therapy in children short. Since comorbidities are not presented in PSD it is unclear which children suffer from PSD; thus, studies are necessary to identify predisposing factors for PSD. In our study, PSD differs from ASD in diagnostic and especially in therapeutic aspects. Therefore, specific guidelines for PSD would be desirable. MDPI 2022-07-22 /pmc/articles/PMC9331686/ /pubmed/35892606 http://dx.doi.org/10.3390/children9081103 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yagdiran, Ayla
Meyer-Schwickerath, Charlotte
Wolpers, Raphael
Otto-Lambertz, Christina
Mehler, Katrin
Oberthür, Andre
Kernich, Nikolaus
Eysel, Peer
Jung, Norma
Zarghooni, Kourosh
What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title_full What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title_fullStr What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title_full_unstemmed What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title_short What Do We Know about Spondylodiscitis in Children? A Retrospective Study
title_sort what do we know about spondylodiscitis in children? a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331686/
https://www.ncbi.nlm.nih.gov/pubmed/35892606
http://dx.doi.org/10.3390/children9081103
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