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Synthesis of Celecoxib-Eutectic Mixture Particles via Supercritical CO(2) Process and Celecoxib Immediate Release Tablet Formulation by Quality by Design Approach

Significant improvements in the wettability and dissolution rate of celecoxib (CEL), a poorly soluble selective cyclooxygenase-2 (COX-2) inhibitor, have been shown by Huyn et al., 2019 by combining the binary pharmaceutical compositions including CEL and one of the two co-formers, adipic acid (ADI)...

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Detalles Bibliográficos
Autores principales:	Hong, Seung-Hyeon, Dinh, Linh, Abuzar, Sharif Md, Lee, Eun Seok, Hwang, Sung-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331714/ https://www.ncbi.nlm.nih.gov/pubmed/35893805 http://dx.doi.org/10.3390/pharmaceutics14081549

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