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Retinal Toxicity Induced by Chemical Agents

Vision is an important sense for humans, and visual impairment/blindness has a huge impact in daily life. The retina is a nervous tissue that is essential for visual processing since it possesses light sensors (photoreceptors) and performs a pre-processing of visual information. Thus, retinal cell d...

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Autores principales: Souza Monteiro de Araújo, Daniel, Brito, Rafael, Pereira-Figueiredo, Danniel, dos Santos-Rodrigues, Alexandre, De Logu, Francesco, Nassini, Romina, Zin, Andrea, Calaza, Karin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331776/
https://www.ncbi.nlm.nih.gov/pubmed/35897758
http://dx.doi.org/10.3390/ijms23158182
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author Souza Monteiro de Araújo, Daniel
Brito, Rafael
Pereira-Figueiredo, Danniel
dos Santos-Rodrigues, Alexandre
De Logu, Francesco
Nassini, Romina
Zin, Andrea
Calaza, Karin C.
author_facet Souza Monteiro de Araújo, Daniel
Brito, Rafael
Pereira-Figueiredo, Danniel
dos Santos-Rodrigues, Alexandre
De Logu, Francesco
Nassini, Romina
Zin, Andrea
Calaza, Karin C.
author_sort Souza Monteiro de Araújo, Daniel
collection PubMed
description Vision is an important sense for humans, and visual impairment/blindness has a huge impact in daily life. The retina is a nervous tissue that is essential for visual processing since it possesses light sensors (photoreceptors) and performs a pre-processing of visual information. Thus, retinal cell dysfunction or degeneration affects visual ability and several general aspects of the day-to-day of a person’s lives. The retina has a blood–retinal barrier, which protects the tissue from a wide range of molecules or microorganisms. However, several agents, coming from systemic pathways, reach the retina and influence its function and survival. Pesticides are still used worldwide for agriculture, contaminating food with substances that could reach the retina. Natural products have also been used for therapeutic purposes and are another group of substances that can get to the retina. Finally, a wide number of medicines administered for different diseases can also affect the retina. The present review aimed to gather recent information about the hazard of these products to the retina, which could be used to encourage the search for more healthy, suitable, or less risky agents.
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spelling pubmed-93317762022-07-29 Retinal Toxicity Induced by Chemical Agents Souza Monteiro de Araújo, Daniel Brito, Rafael Pereira-Figueiredo, Danniel dos Santos-Rodrigues, Alexandre De Logu, Francesco Nassini, Romina Zin, Andrea Calaza, Karin C. Int J Mol Sci Review Vision is an important sense for humans, and visual impairment/blindness has a huge impact in daily life. The retina is a nervous tissue that is essential for visual processing since it possesses light sensors (photoreceptors) and performs a pre-processing of visual information. Thus, retinal cell dysfunction or degeneration affects visual ability and several general aspects of the day-to-day of a person’s lives. The retina has a blood–retinal barrier, which protects the tissue from a wide range of molecules or microorganisms. However, several agents, coming from systemic pathways, reach the retina and influence its function and survival. Pesticides are still used worldwide for agriculture, contaminating food with substances that could reach the retina. Natural products have also been used for therapeutic purposes and are another group of substances that can get to the retina. Finally, a wide number of medicines administered for different diseases can also affect the retina. The present review aimed to gather recent information about the hazard of these products to the retina, which could be used to encourage the search for more healthy, suitable, or less risky agents. MDPI 2022-07-25 /pmc/articles/PMC9331776/ /pubmed/35897758 http://dx.doi.org/10.3390/ijms23158182 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Souza Monteiro de Araújo, Daniel
Brito, Rafael
Pereira-Figueiredo, Danniel
dos Santos-Rodrigues, Alexandre
De Logu, Francesco
Nassini, Romina
Zin, Andrea
Calaza, Karin C.
Retinal Toxicity Induced by Chemical Agents
title Retinal Toxicity Induced by Chemical Agents
title_full Retinal Toxicity Induced by Chemical Agents
title_fullStr Retinal Toxicity Induced by Chemical Agents
title_full_unstemmed Retinal Toxicity Induced by Chemical Agents
title_short Retinal Toxicity Induced by Chemical Agents
title_sort retinal toxicity induced by chemical agents
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331776/
https://www.ncbi.nlm.nih.gov/pubmed/35897758
http://dx.doi.org/10.3390/ijms23158182
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