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Population Pharmacokinetic and Pharmacodynamic Analysis of Dalbavancin for Long-Term Treatment of Subacute and/or Chronic Infectious Diseases: The Major Role of Therapeutic Drug Monitoring

A population pharmacokinetic analysis of dalbavancin was conducted in patients with different infection sites. Non-linear mixed effect modeling was used for pharmacokinetic analysis and covariate evaluation. Monte Carlo simulations assessed the probability of target attainment (PTA) of total dalbava...

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Detalles Bibliográficos
Autores principales: Cojutti, Pier Giorgio, Tedeschi, Sara, Gatti, Milo, Zamparini, Eleonora, Meschiari, Marianna, Siega, Paola Della, Mazzitelli, Maria, Soavi, Laura, Binazzi, Raffaella, Erne, Elke Maria, Rizzi, Marco, Cattelan, Anna Maria, Tascini, Carlo, Mussini, Cristina, Viale, Pierluigi, Pea, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331863/
https://www.ncbi.nlm.nih.gov/pubmed/35892386
http://dx.doi.org/10.3390/antibiotics11080996