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NMR Assignments of Six Asymmetrical N-Nitrosamine Isomers Determined in an Active Pharmaceutical Ingredient by DFT Calculations

N-nitrosamines, which are well-known pro-mutagens, are found in drugs, pickled food and tobacco. Therefore, controlling their concentrations is very important. When an HPLC, GC or NMR analysis is conducted to investigate certain asymmetrical N-nitrosamines, two sets of signals attributed to the asym...

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Detalles Bibliográficos
Autores principales: Guan, Hao-Yue, Feng, Yu-Fei, Sun, Bai-Hao, Niu, Jian-Zhao, Zhang, Qing-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331877/
https://www.ncbi.nlm.nih.gov/pubmed/35897926
http://dx.doi.org/10.3390/molecules27154749

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