Cargando…
Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331898/ https://www.ncbi.nlm.nih.gov/pubmed/35893099 http://dx.doi.org/10.3390/medicina58080984 |
_version_ | 1784758515064111104 |
---|---|
author | Cimpoca Raptis, Brindusa Ana Panaitescu, Anca Maria Peltecu, Gheorghe Gica, Nicolae Botezatu, Radu Popescu, Mihaela Roxana Macri, Anca Constantin, Ana Pavel, Bogdan |
author_facet | Cimpoca Raptis, Brindusa Ana Panaitescu, Anca Maria Peltecu, Gheorghe Gica, Nicolae Botezatu, Radu Popescu, Mihaela Roxana Macri, Anca Constantin, Ana Pavel, Bogdan |
author_sort | Cimpoca Raptis, Brindusa Ana |
collection | PubMed |
description | Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome. |
format | Online Article Text |
id | pubmed-9331898 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93318982022-07-29 Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation Cimpoca Raptis, Brindusa Ana Panaitescu, Anca Maria Peltecu, Gheorghe Gica, Nicolae Botezatu, Radu Popescu, Mihaela Roxana Macri, Anca Constantin, Ana Pavel, Bogdan Medicina (Kaunas) Review Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome. MDPI 2022-07-23 /pmc/articles/PMC9331898/ /pubmed/35893099 http://dx.doi.org/10.3390/medicina58080984 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Cimpoca Raptis, Brindusa Ana Panaitescu, Anca Maria Peltecu, Gheorghe Gica, Nicolae Botezatu, Radu Popescu, Mihaela Roxana Macri, Anca Constantin, Ana Pavel, Bogdan Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title | Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title_full | Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title_fullStr | Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title_full_unstemmed | Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title_short | Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation |
title_sort | pulmonary alveolar proteinosis and pregnancy: a review of the literature and case presentation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331898/ https://www.ncbi.nlm.nih.gov/pubmed/35893099 http://dx.doi.org/10.3390/medicina58080984 |
work_keys_str_mv | AT cimpocaraptisbrindusaana pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT panaitescuancamaria pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT peltecugheorghe pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT gicanicolae pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT botezaturadu pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT popescumihaelaroxana pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT macrianca pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT constantinana pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation AT pavelbogdan pulmonaryalveolarproteinosisandpregnancyareviewoftheliteratureandcasepresentation |