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Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation

Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for...

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Autores principales: Cimpoca Raptis, Brindusa Ana, Panaitescu, Anca Maria, Peltecu, Gheorghe, Gica, Nicolae, Botezatu, Radu, Popescu, Mihaela Roxana, Macri, Anca, Constantin, Ana, Pavel, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331898/
https://www.ncbi.nlm.nih.gov/pubmed/35893099
http://dx.doi.org/10.3390/medicina58080984
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author Cimpoca Raptis, Brindusa Ana
Panaitescu, Anca Maria
Peltecu, Gheorghe
Gica, Nicolae
Botezatu, Radu
Popescu, Mihaela Roxana
Macri, Anca
Constantin, Ana
Pavel, Bogdan
author_facet Cimpoca Raptis, Brindusa Ana
Panaitescu, Anca Maria
Peltecu, Gheorghe
Gica, Nicolae
Botezatu, Radu
Popescu, Mihaela Roxana
Macri, Anca
Constantin, Ana
Pavel, Bogdan
author_sort Cimpoca Raptis, Brindusa Ana
collection PubMed
description Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome.
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spelling pubmed-93318982022-07-29 Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation Cimpoca Raptis, Brindusa Ana Panaitescu, Anca Maria Peltecu, Gheorghe Gica, Nicolae Botezatu, Radu Popescu, Mihaela Roxana Macri, Anca Constantin, Ana Pavel, Bogdan Medicina (Kaunas) Review Pulmonary Alveolar Proteinosis (PAP) is a rare, usually autoimmune, disease, where surfactant accumulates within alveoli due to decreased clearance, causing dyspnea and hypoxemia. The disease is even more rare in pregnancy; nevertheless, it has been reported in pregnant women and can even appear for the first time during pregnancy as an asthma-like illness. Therefore, awareness is important. Similarly to many autoimmune diseases, it can worsen during pregnancy and postpartum, causing maternal and fetal/neonatal complications. This paper offers a narrative literature review of PAP and pregnancy, while illustrating a case of a pregnant patient with known PAP who developed preeclampsia in the third trimester but had an overall fortunate maternal and neonatal outcome. MDPI 2022-07-23 /pmc/articles/PMC9331898/ /pubmed/35893099 http://dx.doi.org/10.3390/medicina58080984 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cimpoca Raptis, Brindusa Ana
Panaitescu, Anca Maria
Peltecu, Gheorghe
Gica, Nicolae
Botezatu, Radu
Popescu, Mihaela Roxana
Macri, Anca
Constantin, Ana
Pavel, Bogdan
Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title_full Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title_fullStr Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title_full_unstemmed Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title_short Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
title_sort pulmonary alveolar proteinosis and pregnancy: a review of the literature and case presentation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331898/
https://www.ncbi.nlm.nih.gov/pubmed/35893099
http://dx.doi.org/10.3390/medicina58080984
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