Cargando…

Developing a Method to Estimate the Downstream Metabolite Signals from Hyperpolarized [1-(13)C]Pyruvate

Hyperpolarized carbon-13 MRI has the advantage of allowing the study of glycolytic flow in vivo or in vitro dynamically in real-time. The apparent exchange rate constant of a metabolite dynamic signal reflects the metabolite changes of a disease. Downstream metabolites can have a low signal-to-noise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsieh, Ching-Yi, Sung, Cheng-Hsuan, Shen, Yi-Liang (Eric), Lai, Ying-Chieh, Lu, Kuan-Ying, Lin, Gigin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332172/ https://www.ncbi.nlm.nih.gov/pubmed/35897987 http://dx.doi.org/10.3390/s22155480

Ejemplares similares

Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study
por: Lai, Ying-Chieh, et al.
Publicado: (2021)

Synthesis of (13)C and (2)H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate
por: Brahms, Arne, et al.
Publicado: (2022)

Metabolite-Specific Echo-Planar Imaging of Hyperpolarized [1-(13)C]Pyruvate at 4.7 T
por: Blazey, Tyler, et al.
Publicado: (2021)

Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized (13)C-Pyruvate MRI
por: Sahin, Sule I., et al.
Publicado: (2023)

A comparison of quantitative methods for clinical imaging with hyperpolarized (13)C‐pyruvate
por: Daniels, Charlie J., et al.
Publicado: (2016)

Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate
por: Serrao, Eva M., et al.
Publicado: (2016)

Molecular detection of inflammation in cell models using hyperpolarized (13)C-pyruvate
por: Sriram, Renuka, et al.
Publicado: (2018)

Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies
por: Larson, Peder EZ, et al.
Publicado: (2023)

In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized (13)C-Pyruvate
por: Hu, Simon, et al.
Publicado: (2009)

A Catalyzing Phantom for Reproducible Dynamic Conversion of Hyperpolarized [1-(13)C]-Pyruvate
por: Walker, Christopher M., et al.
Publicado: (2013)

Metabolism of hyperpolarized [1‐(13)C]pyruvate through alternate pathways in rat liver
por: Jin, Eunsook S., et al.
Publicado: (2016)

Effects of fasting on serial measurements of hyperpolarized [1‐(13)C]pyruvate metabolism in tumors
por: Serrao, Eva M., et al.
Publicado: (2016)

Hyperpolarized [1‐(13)C] pyruvate as a possible diagnostic tool in liver disease
por: Kjærgaard, Uffe, et al.
Publicado: (2018)

Detecting de novo Hepatic Ketogenesis Using Hyperpolarized [2-(13)C] Pyruvate
por: Ragavan, Mukundan, et al.
Publicado: (2022)

Lactate saturation limits bicarbonate detection in hyperpolarized (13)C‐pyruvate MRI of the brain
por: Bøgh, Nikolaj, et al.
Publicado: (2022)

Detection of 3D Cardiac metabolism after injection of hyperpolarized [1-13C]pyruvate
por: Frijia, Francesca, et al.
Publicado: (2011)

Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Clinical translation of hyperpolarized (13)C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging
por: Qin, Hecong, et al.
Publicado: (2021)

Imaging Neurodegenerative Metabolism in Amyotrophic Lateral Sclerosis with Hyperpolarized [1-(13)C]pyruvate MRI
por: Bøgh, Nikolaj, et al.
Publicado: (2022)

Assessing the effect of anesthetic gas mixtures on hyperpolarized (13) C pyruvate metabolism in the rat brain
por: Healicon, Richard, et al.
Publicado: (2022)

Hyperpolarized (13)C MRI Reveals Large Changes in Pyruvate Metabolism During Digestion in Snakes
por: Hansen, Kasper, et al.
Publicado: (2022)

LIGHT-SABRE Hyperpolarizes 1-(13)C-Pyruvate Continuously without Magnetic Field Cycling
por: Pravdivtsev, Andrey N., et al.
Publicado: (2023)

Age‐associated change in pyruvate metabolism investigated with hyperpolarized (13)C‐MRI of the human brain
por: Uthayakumar, Biranavan, et al.
Publicado: (2023)

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse
por: Marco-Rius, Irene, et al.
Publicado: (2013)

(13)C magnetic resonance spectroscopy measurements with hyperpolarized [1‐(13)C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo
por: Dzien, Piotr, et al.
Publicado: (2015)

Evaluation of Hyperpolarized [1-(13)C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time
por: Sandulache, Vlad C., et al.
Publicado: (2014)

Probing Early Tumor Response to Radiation Therapy Using Hyperpolarized [1-(13)C]pyruvate in MDA-MB-231 Xenografts
por: Chen, Albert P., et al.
Publicado: (2013)

3D cardiac Chemical Shift Imaging of [1-13C] hyperpolarized acetate and pyruvate in pigs
por: Menichetti, Luca, et al.
Publicado: (2013)

Modeling non‐linear kinetics of hyperpolarized [1‐(13)C] pyruvate in the crystalloid‐perfused rat heart
por: Mariotti, E., et al.
Publicado: (2016)

Assessment of Metformin induced changes in cardiac redox state using hyperpolarized[1-(13)C]pyruvate
por: Lewis, Andrew, et al.
Publicado: (2016)

Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-(13)C]pyruvate
por: Harris, Talia, et al.
Publicado: (2018)

Hyperpolarized (13)C Diffusion MRS of Co-Polarized Pyruvate and Fumarate to Measure Lactate Export and Necrosis
por: Feuerecker, Benedikt, et al.
Publicado: (2017)

Evaluation of Active Brown Adipose Tissue by the Use of Hyperpolarized [1-(13)C]Pyruvate MRI in Mice
por: Riis-Vestergaard, Mette Ji, et al.
Publicado: (2018)

Metabolic imaging of energy metabolism in traumatic brain injury using hyperpolarized [1-(13)C]pyruvate
por: DeVience, Stephen J., et al.
Publicado: (2017)

Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1‐13C]pyruvate
por: Lau, Angus Z., et al.
Publicado: (2016)

Assessment of Aspartate and Bicarbonate Produced From Hyperpolarized [1-(13)C]Pyruvate as Markers of Renal Gluconeogenesis
por: Yoshihara, Hikari A. I., et al.
Publicado: (2021)

Initial Experience on Hyperpolarized [1-(13)C]Pyruvate MRI Multicenter Reproducibility—Are Multicenter Trials Feasible?
por: Bøgh, Nikolaj, et al.
Publicado: (2022)

Transportable hyperpolarized metabolites
por: Ji, Xiao, et al.
Publicado: (2017)

Correction: Probing Early Tumor Response to Radiation Therapy Using Hyperpolarized [1-(13)C]pyruvate in MDA-MB-231 Xenografts
por: Chen, Albert P., et al.
Publicado: (2013)

[(13)C]bicarbonate labelled from hyperpolarized [1-(13)C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
por: Can, Emine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s0d30fvt86m6cp8nrv9004nr6l