Cargando…
Hyperinsulinemic Hypoglycemia Associated with a Ca(V)1.2 Variant with Mixed Gain- and Loss-of-Function Effects
The voltage-dependent L-type calcium channel isoform Ca(V)1.2 is critically involved in many physiological processes, e.g., in cardiac action potential formation, electromechanical coupling and regulation of insulin secretion by beta cells. Gain-of-function mutations in the calcium voltage-gated cha...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332183/ https://www.ncbi.nlm.nih.gov/pubmed/35897673 http://dx.doi.org/10.3390/ijms23158097 |