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Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize b...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332295/ https://www.ncbi.nlm.nih.gov/pubmed/35892335 http://dx.doi.org/10.3390/biom12081025 |
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author | Zorrilla, Jesús G. Evidente, Antonio |
author_facet | Zorrilla, Jesús G. Evidente, Antonio |
author_sort | Zorrilla, Jesús G. |
collection | PubMed |
description | Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize bioactive alkaloids, such as animals, marine organisms, bacteria, and fungi. This review covers the findings of the last 20 years (2002–2022) related to the isolation, structures, and biological activities of the alkaloids produced by mushrooms, a fungal subgroup, and their potential to develop drugs and agrochemicals. In some cases, the synthesis of the reviewed compounds and structure−activity relationship studies have been described. |
format | Online Article Text |
id | pubmed-9332295 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93322952022-07-29 Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup Zorrilla, Jesús G. Evidente, Antonio Biomolecules Review Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize bioactive alkaloids, such as animals, marine organisms, bacteria, and fungi. This review covers the findings of the last 20 years (2002–2022) related to the isolation, structures, and biological activities of the alkaloids produced by mushrooms, a fungal subgroup, and their potential to develop drugs and agrochemicals. In some cases, the synthesis of the reviewed compounds and structure−activity relationship studies have been described. MDPI 2022-07-24 /pmc/articles/PMC9332295/ /pubmed/35892335 http://dx.doi.org/10.3390/biom12081025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zorrilla, Jesús G. Evidente, Antonio Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title | Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title_full | Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title_fullStr | Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title_full_unstemmed | Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title_short | Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup |
title_sort | structures and biological activities of alkaloids produced by mushrooms, a fungal subgroup |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332295/ https://www.ncbi.nlm.nih.gov/pubmed/35892335 http://dx.doi.org/10.3390/biom12081025 |
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