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Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup

Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize b...

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Detalles Bibliográficos
Autores principales: Zorrilla, Jesús G., Evidente, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332295/
https://www.ncbi.nlm.nih.gov/pubmed/35892335
http://dx.doi.org/10.3390/biom12081025
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author Zorrilla, Jesús G.
Evidente, Antonio
author_facet Zorrilla, Jesús G.
Evidente, Antonio
author_sort Zorrilla, Jesús G.
collection PubMed
description Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize bioactive alkaloids, such as animals, marine organisms, bacteria, and fungi. This review covers the findings of the last 20 years (2002–2022) related to the isolation, structures, and biological activities of the alkaloids produced by mushrooms, a fungal subgroup, and their potential to develop drugs and agrochemicals. In some cases, the synthesis of the reviewed compounds and structure−activity relationship studies have been described.
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spelling pubmed-93322952022-07-29 Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup Zorrilla, Jesús G. Evidente, Antonio Biomolecules Review Alkaloids are a wide family of basic N-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize bioactive alkaloids, such as animals, marine organisms, bacteria, and fungi. This review covers the findings of the last 20 years (2002–2022) related to the isolation, structures, and biological activities of the alkaloids produced by mushrooms, a fungal subgroup, and their potential to develop drugs and agrochemicals. In some cases, the synthesis of the reviewed compounds and structure−activity relationship studies have been described. MDPI 2022-07-24 /pmc/articles/PMC9332295/ /pubmed/35892335 http://dx.doi.org/10.3390/biom12081025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zorrilla, Jesús G.
Evidente, Antonio
Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title_full Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title_fullStr Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title_full_unstemmed Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title_short Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup
title_sort structures and biological activities of alkaloids produced by mushrooms, a fungal subgroup
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332295/
https://www.ncbi.nlm.nih.gov/pubmed/35892335
http://dx.doi.org/10.3390/biom12081025
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