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Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTD

Mutations in the spike protein of SARS-CoV-2 can lead to evasion from neutralizing antibodies and affect the efficacy of passive and active immunization strategies. Immunization of mice harboring an entire set of human immunoglobulin variable region gene segments allowed to identify nine neutralizin...

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Detalles Bibliográficos
Autores principales: Peter, Antonia Sophia, Grüner, Eva, Socher, Eileen, Fraedrich, Kirsten, Richel, Elie, Mueller-Schmucker, Sandra, Cordsmeier, Arne, Ensser, Armin, Sticht, Heinrich, Überla, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332373/
https://www.ncbi.nlm.nih.gov/pubmed/35897753
http://dx.doi.org/10.3390/ijms23158177