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Prenylation Defects and Oxidative Stress Trigger the Main Consequences of Neuroinflammation Linked to Mevalonate Pathway Deregulation

The cholesterol biosynthesis represents a crucial metabolic pathway for cellular homeostasis. The end products of this pathway are sterols, such as cholesterol, which are essential components of cell membranes, precursors of steroid hormones, bile acids, and other molecules such as ubiquinone. Furth...

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Detalles Bibliográficos
Autores principales: Pisanti, Simona, Rimondi, Erika, Pozza, Elena, Melloni, Elisabetta, Zauli, Enrico, Bifulco, Maurizio, Martinelli, Rosanna, Marcuzzi, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332440/
https://www.ncbi.nlm.nih.gov/pubmed/35897423
http://dx.doi.org/10.3390/ijerph19159061