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Coaxial Synthesis of PEI-Based Nanocarriers of Encapsulated RNA-Therapeutics to Specifically Target Muscle Cells

In this work, we performed a methodological comparative analysis to synthesize polyethyleneimine (PEI) nanoparticles using (i) conventional nanoprecipitation (NP), (ii) electrospraying (ES), and (iii) coaxial electrospraying (CA). The nanoparticles transported antisense oligonucleotides (ASOs), eith...

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Detalles Bibliográficos
Autores principales: de la Hoz, Raquel, Diban, Nazely, Berciano, María T., San Emeterio, Carlos, Urtiaga, Ane, Lafarga, Miguel, Rodríguez-Rey, José C., Tapia, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332584/
https://www.ncbi.nlm.nih.gov/pubmed/35892322
http://dx.doi.org/10.3390/biom12081012

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