Cargando…
Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study
Studies on the relation between selenium intake and cognitive function are inconclusive. This study aimed to examine the associations between dietary selenium intake and cognitive function among Chinese adults and tested the interaction effect of selenium intake and iron intake on cognition. Data fr...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332607/ https://www.ncbi.nlm.nih.gov/pubmed/35893861 http://dx.doi.org/10.3390/nu14153005 |
_version_ | 1784758689377288192 |
---|---|
author | Jiang, Ke Xie, Changxiao Li, Zhourong Zeng, Huan Zhao, Yong Shi, Zumin |
author_facet | Jiang, Ke Xie, Changxiao Li, Zhourong Zeng, Huan Zhao, Yong Shi, Zumin |
author_sort | Jiang, Ke |
collection | PubMed |
description | Studies on the relation between selenium intake and cognitive function are inconclusive. This study aimed to examine the associations between dietary selenium intake and cognitive function among Chinese adults and tested the interaction effect of selenium intake and iron intake on cognition. Data from 4852 adults aged 55 years and above who attended the 1991–2006 China Health and Nutrition Survey (CHNS) were used. Cognitive function was assessed through face-to-face interviews in 1997, 2000, 2004, and 2006. A 3-day, 24-hour recall was used to collect dietary selenium intake. Multivariable mixed linear regression and logistic regression were used in the analyses. In fully adjusted regression models, the regression coefficients (95% confidence interval) were 0.00, 0.29 (−0.12–0.70), 0.26 (−0.18–0.70), and 0.50 (0.02–0.97) across the quartiles of selenium intake. In the subgroup analysis, the positive association between selenium intake and cognitive function was only observed in the participants who live in the southern region but not those in the northern region. The selenium-intake-to-iron-intake ratio was inversely associated with low global cognition scores. Furthermore, only those with a normal BMI had a positive association between selenium and cognition. In conclusion, high selenium intake was linked to better cognitive function and a lower risk of cognition decline in Chinese adults among those with low iron intake. A substantial interaction was found between selenium intake and BMI or region. |
format | Online Article Text |
id | pubmed-9332607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93326072022-07-29 Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study Jiang, Ke Xie, Changxiao Li, Zhourong Zeng, Huan Zhao, Yong Shi, Zumin Nutrients Article Studies on the relation between selenium intake and cognitive function are inconclusive. This study aimed to examine the associations between dietary selenium intake and cognitive function among Chinese adults and tested the interaction effect of selenium intake and iron intake on cognition. Data from 4852 adults aged 55 years and above who attended the 1991–2006 China Health and Nutrition Survey (CHNS) were used. Cognitive function was assessed through face-to-face interviews in 1997, 2000, 2004, and 2006. A 3-day, 24-hour recall was used to collect dietary selenium intake. Multivariable mixed linear regression and logistic regression were used in the analyses. In fully adjusted regression models, the regression coefficients (95% confidence interval) were 0.00, 0.29 (−0.12–0.70), 0.26 (−0.18–0.70), and 0.50 (0.02–0.97) across the quartiles of selenium intake. In the subgroup analysis, the positive association between selenium intake and cognitive function was only observed in the participants who live in the southern region but not those in the northern region. The selenium-intake-to-iron-intake ratio was inversely associated with low global cognition scores. Furthermore, only those with a normal BMI had a positive association between selenium and cognition. In conclusion, high selenium intake was linked to better cognitive function and a lower risk of cognition decline in Chinese adults among those with low iron intake. A substantial interaction was found between selenium intake and BMI or region. MDPI 2022-07-22 /pmc/articles/PMC9332607/ /pubmed/35893861 http://dx.doi.org/10.3390/nu14153005 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jiang, Ke Xie, Changxiao Li, Zhourong Zeng, Huan Zhao, Yong Shi, Zumin Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title | Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title_full | Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title_fullStr | Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title_full_unstemmed | Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title_short | Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study |
title_sort | selenium intake and its interaction with iron intake are associated with cognitive functions in chinese adults: a longitudinal study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332607/ https://www.ncbi.nlm.nih.gov/pubmed/35893861 http://dx.doi.org/10.3390/nu14153005 |
work_keys_str_mv | AT jiangke seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy AT xiechangxiao seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy AT lizhourong seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy AT zenghuan seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy AT zhaoyong seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy AT shizumin seleniumintakeanditsinteractionwithironintakeareassociatedwithcognitivefunctionsinchineseadultsalongitudinalstudy |