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The Local Topological Free Energy of the SARS-CoV-2 Spike Protein

The novel coronavirus SARS-CoV-2 infects human cells using a mechanism that involves binding and structural rearrangement of its Spike protein. Understanding protein rearrangement and identifying specific amino acids where mutations affect protein rearrangement has attracted much attention for drug...

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Detalles Bibliográficos
Autores principales: Baldwin, Quenisha, Sumpter, Bobby, Panagiotou, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332627/
https://www.ncbi.nlm.nih.gov/pubmed/35893978
http://dx.doi.org/10.3390/polym14153014