Development and validation of an LC–MS/MS method for quantification of NC-8 in rat plasma and its application to pharmacokinetic studies

ent-16-Oxobeyeran-19-N-methylureido (NC-8) is a recently synthesized derivative of iso-steviol that showed anti-hepatitis B virus (HBV) activity by disturbing replication and gene expression of the HBV and by inhibiting the host toll-like receptor 2/nuclear factor-κB signaling pathway. To study its...

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Detalles Bibliográficos
Autores principales: Kachingwe, Baxter Hepburn, Uang, Yow-Shieng, Huang, Tsurng-Juhn, Wang, Li-Hsuan, Lin, Shwu-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332635/
https://www.ncbi.nlm.nih.gov/pubmed/29389580
http://dx.doi.org/10.1016/j.jfda.2017.09.003

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