Novel Dicarboximide BK124.1 Breaks Multidrug Resistance and Shows Anticancer Efficacy in Chronic Myeloid Leukemia Preclinical Models and Patients’ CD34(+)/CD38(−) Leukemia Stem Cells

SIMPLE SUMMARY: Chemotherapy is a first line treatment in many cancer types, but the constant exposition to chemotherapeutics often leads to therapy resistance. An example is chronic myeloid leukemia that, due to the use of tyrosine kinase inhibitors such as imatinib, remains manageable, however inc...

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Detalles Bibliográficos
Autores principales: Stukan, Iga, Gryzik, Marek, Hoser, Grażyna, Want, Andrew, Grabowska-Pyrzewicz, Wioleta, Zdioruk, Mikolaj, Napiórkowska, Mariola, Cieślak, Marcin, Królewska-Golińska, Karolina, Nawrot, Barbara, Basak, Grzegorz, Wojda, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332833/
https://www.ncbi.nlm.nih.gov/pubmed/35892900
http://dx.doi.org/10.3390/cancers14153641

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