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Tegaserod Maleate Suppresses the Growth of Gastric Cancer In Vivo and In Vitro by Targeting MEK1/2

SIMPLE SUMMARY: The MAP kinase cascades are the most important oncogenic drivers of human cancers, including gastric cancer, and blocking this pathway with targeted inhibitors is an important antitumor strategy. Tegaserod maleate binds to MEK1 and MEK2, inhibiting kinase activity and thus suppressin...

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Detalles Bibliográficos
Autores principales:	Wang, Zitong, Chen, Yingying, Li, Xiaoyu, Zhang, Yuhan, Zhao, Xiaokun, Zhou, Hao, Lu, Xuebo, Zhao, Lili, Yuan, Qiang, Shi, Yunshu, Zhao, Jimin, Dong, Ziming, Jiang, Yanan, Liu, Kangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332868/ https://www.ncbi.nlm.nih.gov/pubmed/35892850 http://dx.doi.org/10.3390/cancers14153592

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