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Role of the PD-1 and PD-L1 axis in COVID-19

Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19.

Detalles Bibliográficos
Autores principales: R Bonam, Srinivasa, Hu, Haitao, Bayry, Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332906/
https://www.ncbi.nlm.nih.gov/pubmed/35899493
http://dx.doi.org/10.2217/fmb-2022-0103
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author R Bonam, Srinivasa
Hu, Haitao
Bayry, Jagadeesh
author_facet R Bonam, Srinivasa
Hu, Haitao
Bayry, Jagadeesh
author_sort R Bonam, Srinivasa
collection PubMed
description Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19.
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spelling pubmed-93329062022-07-29 Role of the PD-1 and PD-L1 axis in COVID-19 R Bonam, Srinivasa Hu, Haitao Bayry, Jagadeesh Future Microbiol Editorial Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19. Future Medicine Ltd 2022-07-27 2022-06 /pmc/articles/PMC9332906/ /pubmed/35899493 http://dx.doi.org/10.2217/fmb-2022-0103 Text en © 2022 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Editorial
R Bonam, Srinivasa
Hu, Haitao
Bayry, Jagadeesh
Role of the PD-1 and PD-L1 axis in COVID-19
title Role of the PD-1 and PD-L1 axis in COVID-19
title_full Role of the PD-1 and PD-L1 axis in COVID-19
title_fullStr Role of the PD-1 and PD-L1 axis in COVID-19
title_full_unstemmed Role of the PD-1 and PD-L1 axis in COVID-19
title_short Role of the PD-1 and PD-L1 axis in COVID-19
title_sort role of the pd-1 and pd-l1 axis in covid-19
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332906/
https://www.ncbi.nlm.nih.gov/pubmed/35899493
http://dx.doi.org/10.2217/fmb-2022-0103
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