Necrosis of uveal melanoma post-COVID-19 vaccination

A 49-year-old Indian male presented with rapidly progressive vision loss 1 day after receiving the second dose of BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine (Pfizer-BioNTech, NY, USA). The eye had secondary angle closure glaucoma, bullous retinal detachment, and massive intraocular he...

Descripción completa

Detalles Bibliográficos
Autores principales: Wagle, Ajeet M., Wu, Bing Cheng, Gopal, Lingam, Sundar, Gangadhara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333048/
https://www.ncbi.nlm.nih.gov/pubmed/35502089
http://dx.doi.org/10.4103/ijo.IJO_3040_21
_version_ 1784758796334137344
author Wagle, Ajeet M.
Wu, Bing Cheng
Gopal, Lingam
Sundar, Gangadhara
author_facet Wagle, Ajeet M.
Wu, Bing Cheng
Gopal, Lingam
Sundar, Gangadhara
author_sort Wagle, Ajeet M.
collection PubMed
description A 49-year-old Indian male presented with rapidly progressive vision loss 1 day after receiving the second dose of BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine (Pfizer-BioNTech, NY, USA). The eye had secondary angle closure glaucoma, bullous retinal detachment, and massive intraocular hemorrhage. Ultrasound showed an ill-defined subretinal mass with moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed an enhancing heterogeneous subretinal mass. Histopathology showed a necrotic melanocytic lesion arising from the posterior edge of the ciliary body and choroid. Necrotic uveal melanoma was confirmed after expert histopathology opinion. Uveal melanomas can rarely present with tumor necrosis following mRNA COVID-19 vaccination.
format Online
Article
Text
id pubmed-9333048
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-93330482022-07-29 Necrosis of uveal melanoma post-COVID-19 vaccination Wagle, Ajeet M. Wu, Bing Cheng Gopal, Lingam Sundar, Gangadhara Indian J Ophthalmol Case Report A 49-year-old Indian male presented with rapidly progressive vision loss 1 day after receiving the second dose of BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine (Pfizer-BioNTech, NY, USA). The eye had secondary angle closure glaucoma, bullous retinal detachment, and massive intraocular hemorrhage. Ultrasound showed an ill-defined subretinal mass with moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed an enhancing heterogeneous subretinal mass. Histopathology showed a necrotic melanocytic lesion arising from the posterior edge of the ciliary body and choroid. Necrotic uveal melanoma was confirmed after expert histopathology opinion. Uveal melanomas can rarely present with tumor necrosis following mRNA COVID-19 vaccination. Wolters Kluwer - Medknow 2022-05 2022-04-28 /pmc/articles/PMC9333048/ /pubmed/35502089 http://dx.doi.org/10.4103/ijo.IJO_3040_21 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Wagle, Ajeet M.
Wu, Bing Cheng
Gopal, Lingam
Sundar, Gangadhara
Necrosis of uveal melanoma post-COVID-19 vaccination
title Necrosis of uveal melanoma post-COVID-19 vaccination
title_full Necrosis of uveal melanoma post-COVID-19 vaccination
title_fullStr Necrosis of uveal melanoma post-COVID-19 vaccination
title_full_unstemmed Necrosis of uveal melanoma post-COVID-19 vaccination
title_short Necrosis of uveal melanoma post-COVID-19 vaccination
title_sort necrosis of uveal melanoma post-covid-19 vaccination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333048/
https://www.ncbi.nlm.nih.gov/pubmed/35502089
http://dx.doi.org/10.4103/ijo.IJO_3040_21
work_keys_str_mv AT wagleajeetm necrosisofuvealmelanomapostcovid19vaccination
AT wubingcheng necrosisofuvealmelanomapostcovid19vaccination
AT gopallingam necrosisofuvealmelanomapostcovid19vaccination
AT sundargangadhara necrosisofuvealmelanomapostcovid19vaccination

Ejemplares similares