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Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders

Concerns have been raised about allergic reactions to messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccines. A history of allergic reactions, including anaphylaxis to drugs, has been frequently reported in individuals with anaphylaxis to mRNA vaccines. To estimate the rate o...

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Autores principales: Marković, Ivan, Božan, Marina, Perković, Tomislav, Paušek, Katarina, Nedeljković, Vanja, Perković, Marina, Kelava, Tomislav, Artuković, Marinko, Stipić Marković, Asja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333079/
https://www.ncbi.nlm.nih.gov/pubmed/35905225
http://dx.doi.org/10.1097/MD.0000000000029571
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author Marković, Ivan
Božan, Marina
Perković, Tomislav
Paušek, Katarina
Nedeljković, Vanja
Perković, Marina
Kelava, Tomislav
Artuković, Marinko
Stipić Marković, Asja
author_facet Marković, Ivan
Božan, Marina
Perković, Tomislav
Paušek, Katarina
Nedeljković, Vanja
Perković, Marina
Kelava, Tomislav
Artuković, Marinko
Stipić Marković, Asja
author_sort Marković, Ivan
collection PubMed
description Concerns have been raised about allergic reactions to messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccines. A history of allergic reactions, including anaphylaxis to drugs, has been frequently reported in individuals with anaphylaxis to mRNA vaccines. To estimate the rate of immediate allergic reactions in patients with a history of drug allergy or other allergic disorders. We included adult patients who had received at least 1 dose of an mRNA COVID-19 vaccine at the Special Hospital for Pulmonary Diseases between March 1, 2021, and October 1, 2021, and who reported a history of drug allergy or other allergic diseases (asthma, allergic rhinitis, atopic dermatitis, food or insect venom allergy, mastocytosis, idiopathic anaphylaxis, acute or chronic urticaria, and/or angioedema). Immediate allergic reactions, including anaphylaxis, occurring within 4 hours of vaccination were recorded. Six immediate allergic reactions were noted in the cohort of 1679 patients (0.36%). One patient experienced anaphylaxis (0.06%), which resolved after epinephrine administration, and the other reactions were mild and easily treatable. Most patients with a history of allergies can safely receive an mRNA COVID-19 vaccine, providing adequate observation periods and preparedness to recognize and treat anaphylaxis.
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spelling pubmed-93330792022-08-03 Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders Marković, Ivan Božan, Marina Perković, Tomislav Paušek, Katarina Nedeljković, Vanja Perković, Marina Kelava, Tomislav Artuković, Marinko Stipić Marković, Asja Medicine (Baltimore) Research Article Concerns have been raised about allergic reactions to messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccines. A history of allergic reactions, including anaphylaxis to drugs, has been frequently reported in individuals with anaphylaxis to mRNA vaccines. To estimate the rate of immediate allergic reactions in patients with a history of drug allergy or other allergic disorders. We included adult patients who had received at least 1 dose of an mRNA COVID-19 vaccine at the Special Hospital for Pulmonary Diseases between March 1, 2021, and October 1, 2021, and who reported a history of drug allergy or other allergic diseases (asthma, allergic rhinitis, atopic dermatitis, food or insect venom allergy, mastocytosis, idiopathic anaphylaxis, acute or chronic urticaria, and/or angioedema). Immediate allergic reactions, including anaphylaxis, occurring within 4 hours of vaccination were recorded. Six immediate allergic reactions were noted in the cohort of 1679 patients (0.36%). One patient experienced anaphylaxis (0.06%), which resolved after epinephrine administration, and the other reactions were mild and easily treatable. Most patients with a history of allergies can safely receive an mRNA COVID-19 vaccine, providing adequate observation periods and preparedness to recognize and treat anaphylaxis. Lippincott Williams & Wilkins 2022-07-29 /pmc/articles/PMC9333079/ /pubmed/35905225 http://dx.doi.org/10.1097/MD.0000000000029571 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Marković, Ivan
Božan, Marina
Perković, Tomislav
Paušek, Katarina
Nedeljković, Vanja
Perković, Marina
Kelava, Tomislav
Artuković, Marinko
Stipić Marković, Asja
Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title_full Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title_fullStr Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title_full_unstemmed Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title_short Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders
title_sort incidence of immediate allergic reactions to mrna covid-19 vaccines in adults with drug allergies and other allergic disorders
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333079/
https://www.ncbi.nlm.nih.gov/pubmed/35905225
http://dx.doi.org/10.1097/MD.0000000000029571
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