Cargando…
Use of Tox21 Screening Data to Evaluate the COVID-19 Drug Candidates for Their Potential Toxic Effects and Related Pathways
Currently, various potential therapeutic agents for coronavirus disease-2019 (COVID-19), a global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are being investigated worldwide mainly through the drug repurposing approach. Several anti-viral, anti-bacterial, an...
Autores principales: | Sakamuru, Srilatha, Huang, Ruili, Xia, Menghang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333127/ https://www.ncbi.nlm.nih.gov/pubmed/35910344 http://dx.doi.org/10.3389/fphar.2022.935399 |
Ejemplares similares
-
Modelling the Tox21 10 K chemical profiles for in vivo toxicity
prediction and mechanism characterization
por: Huang, Ruili, et al.
Publicado: (2016) -
Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition
por: Li, Shuaizhang, et al.
Publicado: (2021) -
Bioactivity Signatures of Drugs vs. Environmental Chemicals Revealed by Tox21 High-Throughput Screening Assays
por: Ngan, Deborah K., et al.
Publicado: (2019) -
Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library
por: Paul-Friedman, Katie, et al.
Publicado: (2019) -
Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform
por: Kabir, Md, et al.
Publicado: (2022)