Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9)

Late-onset non-syndromic autosomal dominant hearing loss 9 (DFNA9) is a hearing impairment caused by mutations in the coagulation factor C homology gene (COCH). COCH encodes for cochlin, a major component of the cochlear extracellular matrix. Though biochemical and genetic studies have characterized...

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Detalles Bibliográficos
Autores principales: Honda, Tomoko, Kawasaki, Norihito, Yanagihara, Rei, Tamura, Ryo, Murakami, Karin, Ichimiya, Tomomi, Matsumoto, Naoki, Nishihara, Shoko, Yamamoto, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333281/
https://www.ncbi.nlm.nih.gov/pubmed/35901072
http://dx.doi.org/10.1371/journal.pone.0268485

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