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NXP031 prevents dopaminergic neuronal loss and oxidative damage in the AAV-WT-α-synuclein mouse model of Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disease characterized by inclusions of aggregated α-synuclein (α-Syn). Oxidative stress plays a critical role in nigrostriatal degeneration and is responsible for α-Syn aggregation in PD. Vitamin C or ascorbic acid acts as an effective antioxidant to p...

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Detalles Bibliográficos
Autores principales:	Song, Min Kyung, Adams, Levi, Lee, Joo Hee, Kim, Yoon-Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333296/ https://www.ncbi.nlm.nih.gov/pubmed/35901090 http://dx.doi.org/10.1371/journal.pone.0272085

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