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N-acetyl cysteine prevents arecoline-inhibited C2C12 myoblast differentiation through ERK1/2 phosphorylation

Arecoline is known to induce reactive oxygen species (ROS). Our previous studies showed that arecoline inhibited myogenic differentiation and acetylcholine receptor cluster formation of C2C12 myoblasts. N-acetyl-cysteine (NAC) is a known ROS scavenger. We hypothesize that NAC scavenges the excess RO...

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Detalles Bibliográficos
Autores principales: Li, Yi-Xuan, Hsiao, Chun-Hung, Chang, Yung-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333315/
https://www.ncbi.nlm.nih.gov/pubmed/35901044
http://dx.doi.org/10.1371/journal.pone.0272231

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