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Sex‐Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca(2+) Handling

BACKGROUND: Sex‐specific differences in vasodilation are mediated in part by differences in cytosolic Ca(2+) handling, but how variations in mitochondrial Ca(2+) contributes to this effect remains unknown. Here, we investigated the extent to which mitochondrial Ca(2+) entry via the MCU (mitochondria...

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Detalles Bibliográficos
Autores principales: Damacena de Angelis, Celio, Endoni, Benney T., Nuno, Daniel, Lamping, Kathryn, Ledolter, Johannes, Koval, Olha M., Grumbach, Isabella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333382/
https://www.ncbi.nlm.nih.gov/pubmed/35766269
http://dx.doi.org/10.1161/JAHA.121.023912